Fig. 1

Boxplot diagrams for comparison of metabolic parameters and liver enzymes, in age and BMI matched GD and GND males and females. Homogenous subpopulations were formed for group comparisons between GD and GND groups with Wilcoxon test (GD males n = 26, GND males n = 60, GD females n = 58, GND males n = 91). No significant differences were measured between age, BMI, abdominal circumference between GD and GND groups. Moreover body fat percentage, insulin sensitivity (M3), OGTT-glucose, estradiol, testosterone and FSH levels did not differ significantly between groups (data not shown). Even small or moderate alcohol consumption was excluded. In age and BMI matched GD males ALT, adiponectin and IL-6 values were significantly higher than in GND males. Further significant differences were found in HDL-C in males. In females no significant difference was noted, except for IL-6, which was border significant (p = 0.063)