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- Acarviosin is a sugar composed of cyclohexitol linked to a 4-amino-4,6-dideoxy-D-glucopyranose. Acarviosin is part of the potent α-amylase inhibitor acarbose and its derivatives. Acarviosin is a product of the degradation of acarbose by gut microbiota, the glycoside hydrolase from gut bacteria Lactobacillus plantarum is able to hydrolyze acarbose to maltose and acarviosin. The nitrogen atom binds to α-amylase more tightly than the natural substrate making it more potent than other inhibitors. Several other acarviosin-containing α-amylase inhibitors have been found in microbes including and from Streptomyces luteogriseus and longer oligosaccharides from Streptomyces coelicoflavus. (en)
- アカルビオシン(Acarviosin)は、が4-アミノ-4,6-ジデオキシ-D-グルコピラノースに結合した二糖である。強いα-アミラーゼ阻害剤であるアカルボース及びその誘導体の構成要素である。窒素原子が、天然の基質よりも強くα-アミラーゼに結合するため、他の阻害剤よりも強力になっている。アカルビオシンを含む他のα-アミラーゼ阻害剤は、微生物Streptomyces luteogriseusのや、またStreptomyces coelicoflavusのより長いオリゴ糖等で見られる。 (ja)
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- (1R,2R,3S,6R)-4-(Hydroxymethyl)-6-{[(2R,3S,4S,5R,6S)-6-methoxy-2-methyl-4,5-dihydroxyoxan-3-yl]amino}cyclohex-4-ene-1,2,3-triol (en)
- Methyl 4,6-dideoxy-4-{[(1R,4S,5R,6R)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-α-(D)-glucopyranoside (en)
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- 4294 (xsd:nonNegativeInteger)
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- Methyl 4,6-dideoxy-4-{[-4,5,6-trihydroxy-3-cyclohex-2-en-1-yl]amino}-α-(D)-glucopyranoside (en)
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- Acarviosin is a sugar composed of cyclohexitol linked to a 4-amino-4,6-dideoxy-D-glucopyranose. Acarviosin is part of the potent α-amylase inhibitor acarbose and its derivatives. Acarviosin is a product of the degradation of acarbose by gut microbiota, the glycoside hydrolase from gut bacteria Lactobacillus plantarum is able to hydrolyze acarbose to maltose and acarviosin. The nitrogen atom binds to α-amylase more tightly than the natural substrate making it more potent than other inhibitors. Several other acarviosin-containing α-amylase inhibitors have been found in microbes including and from Streptomyces luteogriseus and longer oligosaccharides from Streptomyces coelicoflavus. (en)
- アカルビオシン(Acarviosin)は、が4-アミノ-4,6-ジデオキシ-D-グルコピラノースに結合した二糖である。強いα-アミラーゼ阻害剤であるアカルボース及びその誘導体の構成要素である。窒素原子が、天然の基質よりも強くα-アミラーゼに結合するため、他の阻害剤よりも強力になっている。アカルビオシンを含む他のα-アミラーゼ阻害剤は、微生物Streptomyces luteogriseusのや、またStreptomyces coelicoflavusのより長いオリゴ糖等で見られる。 (ja)
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- Acarviosin (en)
- アカルビオシン (ja)
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