About: HLA-DQ4

An Entity of Type: ethnic group, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

HLA-DQ4 (DQ4) is a serotype subgroup within HLA-DQ(DQ) serotypes. The serotype is determined by the antibody recognition of β4 subset of DQ β-chains. The β-chain of DQ is encoded by HLA-DQB1 locus and DQ4 are encoded by the HLA-DQB1*04 allele group. This group currently contains 2 common alleles, DQB1*0401 and DQB1*0402. HLA-DQ4 and HLA-DQB1*04 are almost synonymous in meaning. DQ4 β-chains combine with α-chains, encoded by genetically linked HLA-DQA1 alleles, to form the cis-haplotype isoforms. These isoforms, nicknamed DQ4.3 and DQ4.4, are also encoded by the DQA1*0303 and DQA1*0401 genes, respectively.

Property	Value
dbo:abstract	HLA-DQ4 (DQ4) is a serotype subgroup within HLA-DQ(DQ) serotypes. The serotype is determined by the antibody recognition of β4 subset of DQ β-chains. The β-chain of DQ is encoded by HLA-DQB1 locus and DQ4 are encoded by the HLA-DQB104 allele group. This group currently contains 2 common alleles, DQB10401 and DQB10402. HLA-DQ4 and HLA-DQB104 are almost synonymous in meaning. DQ4 β-chains combine with α-chains, encoded by genetically linked HLA-DQA1 alleles, to form the cis-haplotype isoforms. These isoforms, nicknamed DQ4.3 and DQ4.4, are also encoded by the DQA10303 and DQA10401 genes, respectively. (en)
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dbp:allele1b	[[#DQB1*0401 (en)
dbp:allele2a	*0303 (en)
dbp:allele2b	[[#DQB1*0402 (en)
dbp:allele3b	*0402 (en)
dbp:imageSource	Illustration of HLA-DQ with gliadin peptide in the binding pocket. (en)
dbp:isoform	DQ α3β4.1 (en) DQ α3β4.2 (en) DQ α4β4.2 (en)
dbp:isoformcount	3 (xsd:integer)
dbp:isoformgroup	HLA-DQ4 (en)
dbp:nick	DQ4.3b (en) [[#DQ4.2 (en) [[#DQ4.3 (en)
dbp:polymerType	MHC Class II, DQ cell surface antigen (en)
dbp:subunit	dbr:HLA-DQB1 dbr:HLA-DQA1
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dcterms:subject	dbc:MHC_class_II dbc:HLA-DQ_haplotypes
gold:hypernym	dbr:Subgroup
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rdfs:comment	HLA-DQ4 (DQ4) is a serotype subgroup within HLA-DQ(DQ) serotypes. The serotype is determined by the antibody recognition of β4 subset of DQ β-chains. The β-chain of DQ is encoded by HLA-DQB1 locus and DQ4 are encoded by the HLA-DQB104 allele group. This group currently contains 2 common alleles, DQB10401 and DQB10402. HLA-DQ4 and HLA-DQB104 are almost synonymous in meaning. DQ4 β-chains combine with α-chains, encoded by genetically linked HLA-DQA1 alleles, to form the cis-haplotype isoforms. These isoforms, nicknamed DQ4.3 and DQ4.4, are also encoded by the DQA10303 and DQA10401 genes, respectively. (en)
rdfs:label	HLA-DQ4 (en)
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prov:wasDerivedFrom	wikipedia-en:HLA-DQ4?oldid=1116878198&ns=0
foaf:depiction	wiki-commons:Special:FilePath/DQ_Illustration.png
foaf:isPrimaryTopicOf	wikipedia-en:HLA-DQ4
is dbo:wikiPageWikiLink of	dbr:Major_histocompatibility_complex,_class_II,_DQ_alpha_1 dbr:HLA-DQ dbr:HLA-DQB1 dbr:HLA-DR4 dbr:HLA-DR8 dbr:DQ4
is foaf:primaryTopic of	wikipedia-en:HLA-DQ4