About: Tipifarnib
An Entity of Type: chemical substance,
from Named Graph: http://dbpedia.org,
within Data Space: dbpedia.org
Tipifarnib (INN, proposed trade name Zarnestra) is a farnesyltransferase inhibitor. Farnesyltransferase inhibitors block the activity of the farnesyltransferase enzyme by inhibiting prenylation of the CAAX tail motif, which ultimately prevents Ras from binding to the membrane, rendering it inactive.
