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ENZYME

ENZYME entry: EC 3.1.21.1

Accepted Name
deoxyribonuclease I
Alternative Name(s)
DNase
pancreatic DNase
thymonuclease
Reaction catalysed
Endonucleolytic cleavage to 5'-phosphodinucleotide and 5'-phosphooligonucleotide end-products
Comment(s)
  • Preference for double-stranded DNA.
  • Similar enzymes: streptococcal DNase (streptodornase), T4 endonuclease II, T7 endonuclease II, Escherichia coli endonuclease I, 'nicking' nuclease of calf thymus, colicin E2 and E3.
  • Formerly EC 3.1.4.5.
Cross-references
BRENDA3.1.21.1
EC2PDB3.1.21.1
ExplorEnz3.1.21.1
KEGG Ligand Database for Enzyme Nomenclature3.1.21.1
IUBMB Enzyme Nomenclature3.1.21.1
MEDLINEFind literature relating to 3.1.21.1
MetaCyc3.1.21.1
Rhea expert-curated reactions3.1.21.1
UniProtKB/Swiss-Prot
U2UMQ6, CS12A_ACISBA0Q7Q2, CS12A_FRATNP00639, DNAS1_BOVIN
Q767J3, DNAS1_CANLFQ9YGI5, DNAS1_CHICKQ4AEE3, DNAS1_HORSE
P24855, DNAS1_HUMANP49183, DNAS1_MOUSEO42446, DNAS1_OREMO
P11936, DNAS1_PIGO18998, DNAS1_RABITP21704, DNAS1_RAT
P11937, DNAS1_SHEEPP26295, DRN1_STREQP57487, END1_BUCAI
Q89AD7, END1_BUCBPP25736, END1_ECOLIQ9I733, TSE7_PSEAE

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.1.21.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-