📢 Scientific Poster Our poster, "Cell Culture Process Development to Reduce High Mannose Glycans in mAb Production" was presented at Chinese Antibody Society conference. Cell culture process development serves as the crucial link in biologics CMC. MAN5 glycan is known to potentially affect the safety and efficacy of biopharmaceuticals. AsymBio’s process development team developed a new and effective cell culture approach which can significantly reduce MAN5 content by up to 78% for a molecule with a high starting MAN5 level of over 30%. The approach demonstrates effectiveness on MAN5 reduction, which can be generally applied for different IgG molecules and numerous projects. To download the poster, please visit: https://lnkd.in/dHtacBGj #asymbio #cellculture #cmc #IgG #antibody #processdevelopment #biologics
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Leap in to this preprint by the team at Abbott which uses ATUM's Leap-In Transposon technology: "Recombinant antibody-producing stable CHOK1 pool stability study." Mammalian cell line stability is an important consideration when establishing a #biologics manufacturing process. Bailin Tu, et al, show how ATUM's platform rapidly generates stable pools that meet manufacturing stability requirements. An important read for anyone doing biologics manufacturing: https://hubs.li/Q02B7zf00 #CellLineDevelopment
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📢 Cell Line Development Webinar Alert 📢 "How to Optimize Stable Cell Line Manufacturing" on Thursday, May 23rd, at 13:00 BST / 14:00 CEST / 08:00 EDT / 05:00 PDT. Join us to hear Dr. Renata Pankiewicz, Cell Line Development Lead for Antibody Manufacturing at FairJourney Biologics, discuss the intricacies of developing a robust and efficient stable cell line using picodroplet technology. Key takeaways: 🔬 Insights into the CLD process at FairJourney Biologics 🛠️ Discover how Cyto-Mine® from Sphere Fluidics revolutionizes the CLD workflow 💡 Unlock the potential of early CLD initiation ➡ Register now to secure your spot and embark on a journey towards optimized cell line development: https://bit.ly/44ymsGd ⬅ Spread the word and tag the colleagues who’d benefit from this invaluable session! #CellLineDevelopment #Biologics #Biopharma #FairJourneyBiologics
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Excited for this one! Should be a really interesting webinar! Follow the link to below for this Free to attend Webinar focusing on Cell Line Development and understanding the opportunity of early CLD initiation!
📢 Cell Line Development Webinar Alert 📢 "How to Optimize Stable Cell Line Manufacturing" on Thursday, May 23rd, at 13:00 BST / 14:00 CEST / 08:00 EDT / 05:00 PDT. Join us to hear Dr. Renata Pankiewicz, Cell Line Development Lead for Antibody Manufacturing at FairJourney Biologics, discuss the intricacies of developing a robust and efficient stable cell line using picodroplet technology. Key takeaways: 🔬 Insights into the CLD process at FairJourney Biologics 🛠️ Discover how Cyto-Mine® from Sphere Fluidics revolutionizes the CLD workflow 💡 Unlock the potential of early CLD initiation ➡ Register now to secure your spot and embark on a journey towards optimized cell line development: https://bit.ly/44ymsGd ⬅ Spread the word and tag the colleagues who’d benefit from this invaluable session! #CellLineDevelopment #Biologics #Biopharma #FairJourneyBiologics
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Don't miss this opportunity to learn how a cutting-edge, high-sensitivity in vitro immunopeptidomics assay can support a more informed and proactive approach to immunogenicity risk assessment in biologics development. 🔗 Register for our upcoming webinar to learn more, featuring a case study from a Lonza expert: https://lnkd.in/gm_Sugy7 #Immunogenicity #Biologics
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You’ve run your biologics discovery program. It’s passed the engineering phase and now you’re considering how to further characterize it. Our “one-stop-shop” for expression, analytics-driven purification, characterization, and developability assessment is what you need. Our biologics team are experts in a plethora of formats, including bs-Ab, ms-Abs, cytokines, non-human antibody formats and antigens. We deliver the right biologics with acute assembly, purity, structural and biophysical characterization, and early developability assessment (non GxP). This approach helps you reach right faster on your downstream applications. Still considering your biologics discovery next steps? Look no further https://lnkd.in/e2V2UJRM #Biologics #ProteinScience #BiologicsDiscovery #DrugDiscovery #DownstreamApplications
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Discover how Cyto-Mine® from Sphere Fluidics revolutionizes the CLD workflow. Join the webinar!!
📢 Cell Line Development Webinar Alert 📢 "How to Optimize Stable Cell Line Manufacturing" on Thursday, May 23rd, at 13:00 BST / 14:00 CEST / 08:00 EDT / 05:00 PDT. Join us to hear Dr. Renata Pankiewicz, Cell Line Development Lead for Antibody Manufacturing at FairJourney Biologics, discuss the intricacies of developing a robust and efficient stable cell line using picodroplet technology. Key takeaways: 🔬 Insights into the CLD process at FairJourney Biologics 🛠️ Discover how Cyto-Mine® from Sphere Fluidics revolutionizes the CLD workflow 💡 Unlock the potential of early CLD initiation ➡ Register now to secure your spot and embark on a journey towards optimized cell line development: https://bit.ly/44ymsGd ⬅ Spread the word and tag the colleagues who’d benefit from this invaluable session! #CellLineDevelopment #Biologics #Biopharma #FairJourneyBiologics
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Don't miss this opportunity to learn how a cutting-edge, high-sensitivity in vitro immunopeptidomics assay can support a more informed and proactive approach to immunogenicity risk assessment in biologics development. 🔗 Register for our upcoming webinar to learn more, featuring a case study from a Lonza expert: https://lnkd.in/eacp_yae #Immunogenicity #Biologics
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ICYMI: Last week our bioassay experts Dr Erika Kovacs, and Dr Rosa Gonzàlez Serrano, Senior Manager, hosted a webinar on “Assessment of Fc-mediated Functional Activity for the Development of Complex Biologics & Bioconjugates.” Key topics included: -Best approaches to assess Fc function (ADCC, ADCP and CDC) for drug discovery and development programs -Benefits of working with experienced clinical research organizations (CROs) to ensure high-quality and reliable data are obtained -Benefits and challenges of complex assay formats like real-time spheroid cytotoxicity assays -How to design and develop successful Fc-mediated functional assays, including the selection of target cell lines, effector cells and appropriate controls Missed the live session? Access the on-demand recording to learn how phase-appropriate strategies help ensure reliable data and robust drug development: https://lnkd.in/e_WNxNmK #Webinar #Biologics #Bioconjugates #DrugDevelopment #Bioassays #CDMO #CRO
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Your Biotherapeutic Discovery: Our First-In-Human Biomanufacturing Experience Just – Evotec Biologics seamlessly integrates services to deliver flexible first-in-human (FIH) programs, supporting our partners from candidate selection to successful Investigative New Drug (IND) submission. We have a proven track record with a range of biotherapeutics including monoclonal antibodies and innovative antibody formats such as bispecifics and Fc-fusion proteins. Our expert scientists and regulatory team are dedicated to guiding our partners to regulatory success. Learn more about our first-in-human services here- https://hubs.ly/Q032d1Hh0 #FIH #First-in-human #Biologics #Biomanufacturing #Antibody
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An impressive poster!