Dorota Gabryś’s Post

How effective is Tumor Treating Fields (TTFields) therapy compared to standard chemotherapy? Novocure's Phase III trial has shown its promise for pancreatic cancer: https://hubs.la/Q02Z-VH90

Survival and inferential analysis in patients with locally advanced breast cancer treated with neoadjuvant chemotherapy and subsequent sentinel lymph node biopsy: prospective single-center study #EJNMMI Reports https://lnkd.in/egavgvu8

Out today #ESMO24! In the non-randomised phase 3b/4 #DESTINY-Breast12 study, #TrastuzumabDeruxtecan (T-DXd) treatment of patients with HER2-positive advanced breast cancer and active or stable #BrainMetastases shows consistent intracranial activity and systemic efficacy of T-DXd. Research by Nadia Harbeck, Nancy Lin et al https://lnkd.in/ehTTtXr3

Role of Neoadjuvant Chemotherapy (NACT) Followed by Surgical Cytoreduction in Advanced Epithelial Ovarian Cancer https://t.co/pQoq2LCcSh #EurekaMag

The concept of Total Neoadjuvant Therapy (TNT) is nebulous in its meaning. This review examines TNT’s reported efficacy for pancreatic cancer with an aim towards improving standardization. https://ja.ma/3xSnQYf

Quantitative dynamic contrast-enhanced (DCE) MRI as a promising method for the prediction of breast cancer response to neoadjuvant chemotherapy (NAC) has been demonstrated mostly in single-center and single-vendor platform studies. Our preliminary study reports the initial experience in implementing quantitative breast DCE-MRI in multi-center (MC) and multi-vendor platform (MP) settings to predict NAC response.  Check out our article published in Frontiers in Oncology:

Postoperative pelvic irradiation combined with concurrent chemotherapy using hypofractionated IMRT with 40 Gy in 16 fractions was safe and well-tolerated in women with cervical cancer, finds nonrandomized controlled trial. https://ja.ma/3Vq30r2

Proton therapy radiation may offer benefits for breast cancer patients by reducing radiation exposure to the heart and lungs. For many, radiation is a key component of treatment. Discover more here: https://lnkd.in/gEPsMuky

Important trial with potentially practice changing results! Will be interesting to see the translational/biomarker data.

You can now read our last paper in Nature Portfolio about novel combination approaches for the treatment of head and neck cancer. https://lnkd.in/et36sTan