Pablo Nenclares’ Post

Datopotamab–deruxtecan in early-stage breast cancer: the sequential multiple assignment randomized I-SPY2.2 phase 2 trial https://lnkd.in/gGn6iw34 #Science #MedicalAdvances

Quantitative dynamic contrast-enhanced (DCE) MRI as a promising method for the prediction of breast cancer response to neoadjuvant chemotherapy (NAC) has been demonstrated mostly in single-center and single-vendor platform studies. Our preliminary study reports the initial experience in implementing quantitative breast DCE-MRI in multi-center (MC) and multi-vendor platform (MP) settings to predict NAC response.  Check out our article published in Frontiers in Oncology:

Advancing Prostate Cancer Diagnosis: [99mTc]Tc-PSMA SPECT/CT Accurate prostate cancer diagnosis is critical, yet limited access to [68Ga]Ga-PSMA PET/CT poses challenges. Recent findings show that [99mTc]Tc-PSMA SPECT/CT offers promising diagnostic accuracy, with 89% sensitivity and 92% specificity. This alternative imaging tool could be particularly valuable in regions with limited PET/CT availability, warranting further validation in larger patient cohorts. #ProstateCancer #MedicalImaging #NuclearMedicine #HealthcareInnovation #SPECTCT #PSMA

An inhibitor for Colorectal Cancer has been investigated, using a mouse model system (refer to ref. 1). (Ref, 1) https://lnkd.in/gTUMKmAi

Authors of a meta-analysis published in the European Journal of Clinical Investigation write in depth about their research on the use of [225Ac]Ac-PSMA in patients with metastatic castration-resistant prostate cancer. They conclude that more research is needed on the effectiveness and safety profile of [225Ac]Ac-PSMA, as well as overall survival and progression-free survival

#PSMA Prostate-Specific Membrane Antigen (PSMA) is revolutionizing how we diagnose and treat prostate cancer. As a highly specific biomarker, PSMA is paving the way for targeted radiotherapies and more accurate diagnostic tools, offering hope for improved patient outcomes. Learn how PSMA is transforming prostate cancer care and the future of precision oncology in our latest blog. 👉 https://lnkd.in/enUZTtMi #ProstateCancer #PSMA #Radiotherapy #PrecisionOncology #CancerDiagnosis #DimaBiotech

I am excited to share our latest research, focusing on the potential of Aripiprazole (ARI) in breast cancer therapy. We explored the therapeutic effects of ARI-loaded niosomes /Chitosan-Au nanoparticles, designed for chemo-photothermal therapy. This approach enhances targeted efficacy while minimizing side effects, showing promise over traditional chemotherapy. #BreastCancerResearch #InnovativeTherapy #NanoMedicine #CancerTreatment #MedicalResearch

Researchers from the ibs.GRANADA Instituto de Investigación Biosanitaria present significant advances in a new therapy against breast cancer in early stages https://lnkd.in/dGCZD4rS

Radiological tumor burden, if shown to have a good prognostic role be easily calculable, could be used in pre-first-line immunotherapy assessment in metastatic clear cell renal cell carcinoma. KidneyCAN https://lnkd.in/ebyTWZJT #kicsm #KCRS24 #cancer #Oncology