Blue Health Intelligence released a brief looking at factors predicting GLP-1 agonist treatment persistence. This particular brief only includes Saxenda (liraglutide 3.0 mg daily) and Wegovy (semaglutide 1.7mg or 2.4mg weekly). I share the most important highlights below. • > 50% of people prescribed one of these drugs for obesity stopped taking it in less than 12 weeks, which would not be enough time to see benefit • People were more likely to continue treatment beyond 12 weeks if the drug was prescribed by an obesity physician or endocrinologist—this might be due to these clinicians being better at coaching patients through the early period when side effects are most common • Patients < 35 years old were less likely to continue treatment past 12 weeks • Patients with the most social vulnerability were the least likely to continue treatment past 12 weeks • Those with more frequent healthcare visits were more likely to continue treatment past 12 weeks This is a health insurance study, not a scientific study. Nonetheless, it suggests that coaching and guidance from medical providers is an important factor in continuing these medications. Link in comments. #obesitymedicine #semaglutide #wegovy #liraglutide #saxenda #obesity
Blue Health Intelligence on GLP-1 agonist treatment persistence
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Ozempic, Wegovy and semaglutide. Mounjaro, Zepbound and tirzepatide. It isn't too often that drug names become media headlines for all the right reasons. We can't deny the hype and enthusiasm that has followed these medications for several years now, but there's a lot that we don't know yet. These innovative treatments are more than just weight-loss aids - they’re transforming how society tackles diabetes, heart disease, and even the risk of many cancers by improving insulin resistance & metabolic health. There are still a few things to figure out: who is the right audience for these medications? How will people combine these drugs with the positive lifestyle changes needed for long-term weight loss? Will the real world evidence be as strong as some of the clinical trials? For the insurance industry, questions around how anti-obesity medication may change underwriting and claims activity are front of mind today. In our latest publication, Prachi Patkee, John Schoonbee and I dive into this and more as we investigate the boom of GLP-1 drugs. Sergio Lopez Jimenez, Natalie Kelly
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1/ Weight loss drugs like Ozempic & Wegovy are more popular, but most physicians haven't been trained to use them https://lnkd.in/e5W4CHbe with CBS News' @AMGreenCBS 2/ Patients need to be monitored for side-effects, such as nausea, vomiting, diarrhea, and abdominal pain, which could be symptoms of serious conditions like pancreatitis or gastroparesis (i.e. stomach paralysis). They should also have regular blood work including blood glucose & kidney function tests. 3/ If a patient's side-effects aren't well managed, they may get discouraged & stop taking the medication, which means that whatever weight they've lost, they're likely to put back on. 4/ If people can't stay on these meds long enough to accrue the long-term health benefits (e.g. reduced risk of cardiovascular disease & stroke, reduced risk of chronic kidney disease), insurance companies may be less likely to cover them.
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Just discovered a fascinating article on the potential impact of GLP-1 medication on society. The future ripples and changes are truly thought-provoking. Check it out! #GLP1 #medication #society #impact
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The current available research notes that 52% of all opioid prescriptions are for patients with low back pain, and over two million Americans suffer from opioid use disorder (OUD), with 47,000 dying from OUD in 2017. In light of the opioid epidemic, the high cost of diagnostic tests and invasive treatment, and the low level of patient satisfaction with such care, researchers from the Boston University School of Public Health set out to find better options for the management of low back pain. Their findings revealed that a patient’s INITIAL choice of healthcare provider plays an important role in their prospects for a successful outcome from the perspective of both the patient and the insurance company.
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The current available research notes that 52% of all opioid prescriptions are for patients with low back pain, and over two million Americans suffer from opioid use disorder (OUD), with 47,000 dying from OUD in 2017. In light of the opioid epidemic, the high cost of diagnostic tests and invasive treatment, and the low level of patient satisfaction with such care, researchers from the Boston University School of Public Health set out to find better options for the management of low back pain. Their findings revealed that a patient’s INITIAL choice of healthcare provider plays an important role in their prospects for a successful outcome from the perspective of both the patient and the insurance company.
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Food for thoughts (pun not intended) The GLP-1 class of anti-obesity drugs like Novo Nordisk’s Wegovy and Eli Lilly’s Zepbound have not only changed the way people think about weight loss, they are also changing the way investors view online obesity clinics. These are suddenly looking like a much more investable prospect. Dietrich Aumann of Helsana HealthInvest, a Swiss health insurance CVC, believes that the medical breakthroughs have given obesity clinics providing GLP-1 drugs an efficacy boost that now makes them scalable businesses. 🫵 Alfio Villani Cristian Ranallo Matteo Centola, PhD PMP® Maria Bobbi https://lnkd.in/dgra7qRu #openinnovation #obesity Mind the Bridge Giovanni Rezzonico Narmina Barukhova
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Access to quality affordable preventive, medical, surgical and palliative care in America is rationed, segregated and inequitably subsidized according location, age, disease, race, job, net worth, sex, job or military status. It doesn’t have to be that way, Bismarck gives all access to quality affordable private insured and private manufactured healthcare. In States That Won’t Pay for Obesity Drugs, ‘They May as Well Have Never Been Created’ https://lnkd.in/ed7SKC2k
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Dr. Haggerty has published a lot of papers, but this may be one of the most important ones. With her research team, she conceptualized it, implemented it, and published it amazingly quickly. Patients around the country are experiencing unprecedented benefits from GLP1 anti-obesity medications only to have access to those medications stripped from them mid-treatment if insurance plans stop coverage. This is the first qualitative study to assess the impact on these patients. Insurances must do better. They should have strategies to get the right people on the right treatments for obesity and should not take people doing well off of treatment. https://lnkd.in/eq5RV97R
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Much of the focus on the impact of GLP-1 receptor agonists (GLP-1s) has been on their long-term health outcomes for people with type 2 diabetes, obesity, and related cardiovascular diseases. However, when making decisions for reimbursement and setting premiums, health insurers need to balance such long-term policyholder health improvements against short- to medium-term increases in claims expenditure. RGA’s latest Global Health Brief explores key considerations and challenges health insurers face and examines actions they might take to benefit policyholders while maintaining a sustainable portfolio.
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Despite being a significant independent risk factor for heart attacks and strokes, and regularly talked about by leading voices in longevity health like Peter Attia, why is Lipoprotein(a), Lp(a) and [pronounced "L P little a") so highly under-measured in the US? About 20% of the US population has a high volume of this largely genetic atherogenic lipoprotein, yet estimates are that only 2% of the population has had their Lp(a) measured. If you think you may be at elevated risk for an ASCVD event (you probably are, whether you admit it or not), ask your healthcare provider to check your Lp(a) at your next doctor's visit. Most insurance doesn't cover the lab test, but your out-of-pocket cost should be about $30 (at most). Learn more here: https://lnkd.in/gs-DrQpV
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10mohttps://www.bcbs.com/sites/default/files/BHI_Issue_Brief_GLP1_Trends.pdf