Icahn School of Medicine at Mount Sinai

We’re thrilled to announce the five-year extension of the National Healthcare Initiative in Guyana, a transformative collaboration with the Government of Guyana, Hess Corporation, and Mount Sinai Health System! This partnership will bring world-class health care to citizens across Guyana, paving the way for a healthier future.   “We’re not just improving health outcomes in Guyana for today—we’re working together to secure a healthier future for generations to come,” said Dr. Rachel Vreeman, Chair of Global Health and Director of the Arnhold Institute for Global Health, Icahn School of Medicine at Mount Sinai.    At yesterday’s signing ceremony, His Excellency Dr. Irfaan Ali, President of Guyana, praised the partnership: “Guyana's health care system will stand as a model of excellence in the Caribbean and beyond. It will become the gold standard for health care services globally.”   Key highlights of the initiative include establishing a National Cancer Center, supporting a new Women’s and Children’s Hospital, expanding community-centered care, advancing a cutting-edge digital health system, modernizing health facilities, training a skilled healthcare workforce -- and much more to elevate health care quality across Guyana.   We’re proud to partner on this groundbreaking effort to build a healthier future for all Guyanese citizens!   Learn more about the initiative:  https://lnkd.in/eDMrXhPd

Dr. Kris White and his team at the White Lab contributed to generating critical antiviral data in both in-vitro and in-vivo models for this innovative project. It is exciting to see this work presented.

Researchers at the Icahn School of Medicine at Mount Sinai have developed a genetic tracing system to tag immune cells that harbor latent HIV, a major barrier to curing the virus. The system, called HIV-1-induced lineage tracing (HILT), permanently marks infected cells, even when the virus is dormant. By using this approach, the team identified nine types of T cells carrying latent HIV and uncovered key genetic pathways that may help the virus persist. This research provides new insights into how HIV hides within the immune system and offers a promising target for future therapies. Dr. Benjamin K. Chen and his team plan to use this system to explore strategies for reactivating and eliminating dormant HIV, bringing the field closer to a potential cure. Read the full study in Nature Communications here: https://mshs.co/4ieH50s

Please join us in congratulating Dr. Katherine T. Chen on being honored as a 2025 Jacobi Medallion Recipient. This prestigious award honors a member of the Mount Sinai community who, through long-term service, has made exceptional contributions to the fields of clinical medicine or biomedical research, or has exemplified extraordinary dedication to Mount Sinai. #JacobiMedallion

🌙 We're excited to share groundbreaking results from our latest research published in the journal Sleep. Our team at Mount Sinai has developed PFTSleep, a foundational transformer AI model trained on full-night, multichannel sleep studies. Remarkably, this model achieves state-of-the-art accuracy in classifying sleep stages across diverse datasets—representing over 1 million hours of polysomnography data! 🛌 Why is this significant? Sleep disorders impact nearly 30% of adults in the U.S., yet only 5% receive accurate diagnoses. Traditional sleep stage classification is time-intensive and subject to human variability. Our AI-driven approach, using representations learned independently from sleep stage classification, offers both precision and scalability. 🤖 The PFTSleep model leverages deep-learning techniques similar to those behind tools like ChatGPT, but tailored specifically for physiological signals collected during sleep. It not only matches expert human scoring but also demonstrates adaptability across multiple cohorts, highlighting its potential for widespread clinical adoption. 📈 We envision that these robust, AI-derived sleep representations will become foundational—not just for accurate sleep stage classification, but also for predicting other important clinical outcomes related to sleep health. 🔗 Curious to explore the full paper? Dive deeper here: https://bit.ly/3ZQw5Y9 https://bit.ly/3ZQw5Y9 💡 We're keen to engage with sleep researchers, clinicians, and AI enthusiasts—your thoughts and insights would be invaluable! Hasso Plattner Institute for Digital Health at Mount Sinai Hasso Plattner InstituteHasso Plattner Foundation Icahn School of Medicine at Mount SinaiMount Sinai Health SystemAI and Human Health at Mount Sinai Benjamin F.Joy Jiang Patricia Kovatch Mayte Suarez-FarinasNeomi Shah Ankit Parekh #AI #SleepResearch #Transformers #DigitalHealth #MountSinai

Congratulations to the Class of 2025 on their residency matches! Forty-five of those students will continue their training at Mount Sinai. We are so proud of your dedication and hard work. Here's to the next chapter! #WeFindAWay #Medicine #MatchDay2025 #MedicalSchool #Residency

We recently gathered to celebrate the 2025 Jacobi Medallion Awards Ceremony, honoring this year’s extraordinary recipients. The Jacobi Medallion is one of the highest distinctions awarded by the Mount Sinai Health System, recognizing individuals who have made exceptional contributions to clinical medicine, biomedical research, or demonstrated unwavering dedication to Mount Sinai. We extend our gratitude to the families, friends, and colleagues who joined us for this special evening, as we celebrated the remarkable achievements of our honorees. Congratulations to the 2025 Jacobi Medallion recipients: Katherine T. Chen, MD, MPH Paul J. Kenny, PhD Adam I. Levine, MD, MSSM '89, MSH '93 Valerie Parkas, MD Rosamond Rhodes, PhD Michelle L. Sainté-Willis Viviana A. Simon, MD, PhD Ashutosh K. Tewari, MBBS, MCh, FRCS (Hon.), DSc (Hon.) Caryn Tiger-Paillex, MSILR James C. Tsai, MD, MBA #JacobiMedallion

Icahn School of Medicine at Mount Sinai student Varun Subramaniam has been selected as a 2025 Gates Cambridge Scholar—one of just 35 students from the U.S. to receive this prestigious honor. The Gates Cambridge Scholarship funds postgraduate study at the University of Cambridge for individuals committed to improving the lives of others through academic excellence and leadership. Varun, a Stanford graduate and FlexMed student at Mount Sinai, is currently pursuing a scholarly year funded through the Neurosurgery Research Fellowship. His research focuses on neuromodulation for neuropsychiatric disorders under the mentorship of Drs. Brian Kopell and Ted Panov at Mount Sinai’s Center for Advanced Circuit Therapeutics. Inspired by pioneers in the field like Dr. Helen Mayberg and Professor Eric Nestler, he aims to advance psychiatric neuromodulation as a neurosurgeon-scientist to help reduce the global burden of mental illness. Beyond research, Varun has been deeply involved in leadership and advocacy, serving on Student Council Steering, the Hospital Ethics Committee, and as National Vice President of TeleHealth Access for Seniors, a nonprofit dedicated to improving healthcare access for older adults. At Cambridge, Varun will pursue a PhD in Psychiatry with Professor Valerie Voon, focusing on the neural networks that drive compulsivity—a fundamental trait implicated in conditions such as OCD, addiction, eating disorders, and autism. By analyzing live human brain recordings, his work will directly inform the development of neuromodulation treatments, offering new hope for individuals affected by these disorders. “I am thrilled to join the Gates Cambridge community. This achievement is as much Mount Sinai’s, my mentors’, as it is mine. The opportunities and mentorship afforded to me by Sinai are nothing short of a blessing. Truly, I am beyond grateful.” Congratulations, Varun! We look forward to seeing the impact of your work. #GatesCambridgeScholar #Neuroscience #MentalHealthResearch

A breakthrough in kidney stone surgery—Mount Sinai’s Department of Urology is redefining percutaneous nephrolithotomy (PCNL) with a totally tubeless, outpatient procedure. This innovation minimizes pain, reduces recovery time, and eliminates hospital stays. Under the leadership of Dr. Mantu Gupta, the technique leverages ultrasound guidance and improved patient positioning for a safer, more efficient approach. Learn how this game-changing technique is improving patient outcomes. Read more here: https://lnkd.in/eEgBe5Qm #Urology #KidneyStones #Innovation

Mount Sinai researchers have discovered molecular glue compounds that protect insulin-producing beta cells from damage linked to type 2 diabetes. By preventing harmful cellular changes, this breakthrough could lead to new treatments that slow or even prevent #diabetes progression—offering hope for improved long-term blood sugar control. Read the full study in Nature here: https://mshs.co/3QIh5OT